Journal of Fisheries 2008-5729 75 3 2022 08 23 Replacement of fish meal by different levels of a food mixture component (consisted of Corn gluten and anchovy fish meal) in diet and their effects on growth indices and liver tissue of Beluga juvenile (Huso huso) Replacement of fish meal by different levels of a food mixture component (consisted of Corn gluten and anchovy fish meal) in diet and their effects on growth indices and liver tissue of Beluga juvenile (Huso huso) 463 480 90258 10.22059/jfisheries.2022.335747.1302 FA Mir Hamed Sayed Hassani Expert, Caspian Sea International Sturgeon Research Institute, Agriculture Research, Education and Extension Organization (AREEO), Rast, Iran. Mir Massoud Sajjadi Professor, Department of Fishery, Faculty of Natural Resources, University of Gillan, Soehsar, Rasht, Iran Ali Hallajian Expert, Caspian Sea International Sturgeon Research Institute, Agriculture Research, Education and Extension Organization (AREEO), Rast, Iran. Bahram Falahatkar Professor, Department of Fishery, Faculty of Natural Resources, University of Gillan, Soehsar, Rasht, Iran Journal Article 2021 12 18 A study carried out for reduction of fish meal in Beluga <em>Huso</em> <em>huso</em> diet. A basic diet based on 54% fish meal were formulated. A mixture based on corn gluten wheat and anchovy fish meal formulated similar to amino acid profile of basic diet at the levels of 20, 40, 60 and 80% as experimental treatments, fish meal (FM) (Basal diet) and corn gluten meal base included 20% replacement (CGM₂₀), 40% replacement (CGM₄₀), 60% replacement (CGM₆₀) and 80% replacement (CGM₈₀) with Similar protein (44%), energy (18 MJ / kg) and amino acid profiles.  Beluga fish (<em>Huso</em> <em>huso</em>) with average weight of 167.6± 6.5g introduced in each experimental unit and were fed on experimental diets during a 10 –week culture period. Effect of these alternatives on growth indicators and liver tissue were investigated. Alternative food had no effect on fish growth indices and there was no significant difference in fish performance growth (P>0.05). No significant difference was observed in hepatosomatic index (P>0.05). Liver tissue was normal in fish fed FM, CGM₂₀, CGM₄₀, CGM₆₀ and a low damage observed in liver tissue such as cell necrosis, nuclear hypertrophy and hemorrhage. But, fish liver tissue fed by CGM₈₀ had higher abnormal liver damages such as lipid degeneration, cell necrosis, biliary stagnation and hemorrhage. . A study carried out for reduction of fish meal in Beluga <em>Huso</em> <em>huso</em> diet. A basic diet based on 54% fish meal were formulated. A mixture based on corn gluten wheat and anchovy fish meal formulated similar to amino acid profile of basic diet at the levels of 20, 40, 60 and 80% as experimental treatments, fish meal (FM) (Basal diet) and corn gluten meal base included 20% replacement (CGM₂₀), 40% replacement (CGM₄₀), 60% replacement (CGM₆₀) and 80% replacement (CGM₈₀) with Similar protein (44%), energy (18 MJ / kg) and amino acid profiles.  Beluga fish (<em>Huso</em> <em>huso</em>) with average weight of 167.6± 6.5g introduced in each experimental unit and were fed on experimental diets during a 10 –week culture period. Effect of these alternatives on growth indicators and liver tissue were investigated. Alternative food had no effect on fish growth indices and there was no significant difference in fish performance growth (P>0.05). No significant difference was observed in hepatosomatic index (P>0.05). Liver tissue was normal in fish fed FM, CGM₂₀, CGM₄₀, CGM₆₀ and a low damage observed in liver tissue such as cell necrosis, nuclear hypertrophy and hemorrhage. But, fish liver tissue fed by CGM₈₀ had higher abnormal liver damages such as lipid degeneration, cell necrosis, biliary stagnation and hemorrhage. . https://jfisheries.ut.ac.ir/article_90258_d55a9cec5a9e432e748381a92fe63f90.pdf